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Short-term low-carbohydrate diet decreases body weight and fat mass but not muscle strength in children and young people with type 1 diabetes

Short-term low-carbohydrate diet decreases body weight and fat mass but not muscle strength in children and young people with type 1 diabetes
  • Zimmermann AT, Lanzinger S, Kummernes SJ, Lund-Blix NA, Holl RW, Frohlich-Reiterer E, et al. Treatment regimens and glycaemic outcomes in more than 100 000 children with type 1 diabetes (2013-22): a longitudinal analysis of data from paediatric diabetes registries. Lancet Diab Endocrinol. 2025;13:47–56.

    CAS 

    Google Scholar 

  • Rawshani A, Sattar N, Franzen S, Rawshani A, Hattersley AT, Svensson AM, et al. Excess mortality and cardiovascular disease in young adults with type 1 diabetes in relation to age at onset: a nationwide, register-based cohort study. Lancet. 2018;392:477–86.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Collaboration NCDRF. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults. Lancet. 2017;390:2627–42.

    Google Scholar 

  • Maffeis C, Birkebaek NH, Konstantinova M, Schwandt A, Vazeou A, Casteels K, et al. Prevalence of underweight, overweight, and obesity in children and adolescents with type 1 diabetes: Data from the international SWEET registry. Pediatr Diab. 2018;19:1211–20.

    CAS 

    Google Scholar 

  • Seckold R, Fisher E, de Bock M, King BR, Smart CE. The ups and downs of low-carbohydrate diets in the management of Type 1 diabetes: a review of clinical outcomes. Diabet Med. 2019;36:326–34.

    CAS 
    PubMed 

    Google Scholar 

  • Ranjan A, Schmidt S, Damm-Frydenberg C, Steineck I, Clausen TR, Holst JJ, et al. Low-carbohydrate diet impairs the effect of glucagon in the treatment of insulin-induced mild hypoglycemia: a randomized crossover study. Diab Care. 2017;40:132–5.

    CAS 

    Google Scholar 

  • de Bock M, Lobley K, Anderson D, Davis E, Donaghue K, Pappas M, et al. Endocrine and metabolic consequences due to restrictive carbohydrate diets in children with type 1 diabetes: an illustrative case series. Pediatr Diab. 2018;19:129–37.

    Google Scholar 

  • Hart M, Pursey K, Smart C. Low carbohydrate diets in eating disorders and type 1 diabetes. Clin Child Psychol Psychiatry. 2021;26:643–55.

    PubMed 

    Google Scholar 

  • Caccavale LJ, Nansel TR, Quick V, Lipsky LM, Laffel LM, Mehta SN. Associations of disordered eating behavior with the family diabetes environment in adolescents with Type 1 diabetes. J Dev Behav Pediatr. 2015;36:8–13.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Groleau V, Schall JI, Stallings VA, Bergqvist CA. Long-term impact of the ketogenic diet on growth and resting energy expenditure in children with intractable epilepsy. Dev Med Child Neurol. 2014;56:898–904.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Annan SF, Higgins LA, Jelleryd E, Hannon T, Rose S, Salis S, et al. ISPAD Clinical Practice Consensus Guidelines 2022: Nutritional management in children and adolescents with diabetes. Pediatr Diab. 2022;23:1297–321.

    Google Scholar 

  • Neuman V, Plachy L, Drnkova L, Pruhova S, Kolouskova S, Obermannova B, et al. Low-carbohydrate diet in children and young people with type 1 diabetes: A randomized controlled trial with cross-over design. Diab Res Clin Pr. 2024;217:111844.

    CAS 

    Google Scholar 

  • Neuman V, Plachy L, Pruhova S, Kolouskova S, Petruzelkova L, Obermannova B, et al. Low-carbohydrate diet among children with type 1 diabetes: a multi-center study. Nutrients. 2021;13. https://doi.org/10.3390/nu13113903.

  • Levran N, Levek N, Gruber N, Afek A, Monsonego-Ornan E, Pinhas-Hamiel O. Low-carbohydrate diet proved effective and safe for youths with type 1 diabetes: A randomised trial. Acta Paediatr. 2025;114:417–27.

    CAS 
    PubMed 

    Google Scholar 

  • Harray AJ, Roberts AG, Crosby NE, Shoneye C, Bebbington K. Experiences and attitudes of parents reducing carbohydrate intake in the management of their child’s type 1 diabetes: a qualitative study. Nutrients. 2023;15. https://doi.org/10.3390/nu15071666.

  • Turton JL, Brinkworth GD, Parker HM, Lim D, Lee K, Rush A, et al. Effects of a low-carbohydrate diet in adults with type 1 diabetes management: A single arm non-randomised clinical trial. PLoS One. 2023;18:e0288440.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar 

  • Wachsmuth NB, Aberer F, Haupt S, Schierbauer JR, Zimmer RT, Eckstein ML, et al. The impact of a high-carbohydrate/low fat vs. low-carbohydrate diet on performance and body composition in physically active adults: a cross-over controlled trial. Nutrients. 2022;14. https://doi.org/10.3390/nu14030423.

  • Gram-Kampmann EM, Hansen CD, Hugger MB, Jensen JM, Brond JC, Hermann AP, et al. Effects of a 6-month, low-carbohydrate diet on glycaemic control, body composition, and cardiovascular risk factors in patients with type 2 diabetes: An open-label randomized controlled trial. Diab Obes Metab. 2022;24:693–703.

    CAS 

    Google Scholar 

  • Lennerz BS, Barton A, Bernstein RK, Dikeman RD, Diulus C, Hallberg S, et al. Management of type 1 diabetes with a very low-carbohydrate diet. Pediatrics. 2018;141. https://doi.org/10.1542/peds.2017-3349.

  • Schulz KF, Altman DG, Moher D, Fergusson D. CONSORT 2010 changes and testing blindness in RCTs. Lancet. 2010;375:1144–6.

    PubMed 

    Google Scholar 

  • Slaughter MH, Lohman TG, Boileau RA, Horswill CA, Stillman RJ, Van Loan MD, et al. Skinfold equations for estimation of body fatness in children and youth. Hum Biol. 1988;60:709–23.

    CAS 
    PubMed 

    Google Scholar 

  • Kobzova J, Vignerova J, Blaha P, Krejcovsky L, Riedlova J. The 6th nationwide anthropological survey of children and adolescents in the Czech Republic in 2001. Cent Eur J Public Health. 2004;12:126–30.

    CAS 
    PubMed 

    Google Scholar 

  • Vanderwall C, Eickhoff J, Randall Clark R, Carrel AL. BMI z-score in obese children is a poor predictor of adiposity changes over time. BMC Pediatr. 2018;18:187.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Veilleux LN, Rauch F. Reproducibility of jumping mechanography in healthy children and adults. J Musculoskelet Neuronal Interact. 2010;10:256–66.

    PubMed 

    Google Scholar 

  • Sumnik Z, Matyskova J, Hlavka Z, Durdilova L, Soucek O, Zemkova D. Reference data for jumping mechanography in healthy children and adolescents aged 6-18 years. J Musculoskelet Neuronal Interact. 2013;13:297–311.

    CAS 
    PubMed 

    Google Scholar 

  • Kawashima S, Sogi C, Kamimura M, Kikuchi A, Kanno J. Severe growth retardation during carbohydrate restriction in type 1 diabetes mellitus: A case report. Clin Pediatr Endocrinol. 2024;33:181–6.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Schmidt S, Christensen MB, Serifovski N, Damm-Frydenberg C, Jensen JB, Floyel T, et al. Low versus high carbohydrate diet in type 1 diabetes: a 12-week randomized open-label crossover study. Diab Obes Metab. 2019;21:1680–8.

    CAS 

    Google Scholar 

  • Maratova K, Soucek O, Matyskova J, Hlavka Z, Petruzelkova L, Obermannova B, et al. Muscle functions and bone strength are impaired in adolescents with type 1 diabetes. Bone. 2018;106:22–7.

    PubMed 

    Google Scholar 

  • Potter AW, Nindl LJ, Soto LD, Pazmino A, Looney DP, Tharion WJ, et al. High precision but systematic offset in a standing bioelectrical impedance analysis (BIA) compared with dual-energy X-ray absorptiometry (DXA). BMJ Nutr Prev Health. 2022;5:254–62.

    PubMed 
    PubMed Central 

    Google Scholar 

  • Buch A, Ben-Yehuda A, Rouach V, Maier AB, Greenman Y, Izkhakov E, et al. Validation of a multi-frequency bioelectrical impedance analysis device for the assessment of body composition in older adults with type 2 diabetes. Nutr Diab. 2022;12:45.

    Google Scholar 

  • Silva AM, Campa F, Stagi S, Gobbo LA, Buffa R, Toselli S, et al. The bioelectrical impedance analysis (BIA) international database: aims, scope, and call for data. Eur J Clin Nutr. 2023;77:1143–50.

    PubMed 

    Google Scholar 

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